منابع مشابه
Pulmonary carcinoid tumors and asbestos exposure.
OBJECTIVES The hypothesis that asbestos exposure may have more specific associations with particular histological types of lung cancer remains controversial. The aim of this study was to analyze the relationships between asbestos exposure and pulmonary carcinoid tumors. METHODS A retrospective case-control study was conducted in 28 cases undergoing surgery for pulmonary carcinoid tumors and a...
متن کاملCarcinoid tumors.
Carcinoid tumors are rare, slow-growing neuroendocrine neoplasms that often are indolent and may not become clinically apparent until there has been metastatic spread or evidence of carcinoid syndrome. Recent evidence has revealed that the overall incidence of carcinoid tumors has been steadily increasing, and although the disease was thought to be relatively benign, it is now considered one of...
متن کاملInfrequent Mutations of the p53 Gene in Pulmonary Carcinoid Tumors
Archival specimens of 25 pulmonary carcinoids including 15 cases of typical carcinoid, 9 atypical carcinoids, and 1 large-cell nenroendocrine carcinoma were analyzed for mutations in exons 5 to 8 of the p53 gene. Mutations were identified in 4 tumors, including 3 out of 15 (20%) typical carcinoids and the single large-cell neuroendocrine carcinoma, but none of the atypical carcinomas showed a m...
متن کاملPulmonary Carcinoid Tumors: The Need for Tailored Assessment
Primary neuroendocrine neoplasms of the lung represent a clinical spectrum of tumors ranging from the relatively benign and slow-growing typical carcinoid to the highly aggressive small-cell lung carcinoma. The rarity of carcinoids has made the role of radiation therapy in their management controversial. This review considers the results of published studies to generate treatment recommendation...
متن کاملAnalysis of ErbB receptors in pulmonary carcinoid tumors.
PURPOSE This study aimed to investigate the expression of the ErbB family of receptor tyrosine kinases in pulmonary typical carcinoid and atypical carcinoid tumors and to understand the role of epidermal growth factor receptor (EGFR) signaling in pulmonary carcinoid tumor proliferation. EXPERIMENTAL DESIGN Surgically resected typical carcinoid (n = 24) and atypical carcinoid (n = 7) tumor tis...
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ژورنال
عنوان ژورنال: Cancer
سال: 2001
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(20010601)91:11<2104::aid-cncr1238>3.0.co;2-i